| Election Name: | 1968 United States Senate election in Colorado |
| Country: | Colorado |
| Type: | Presidential |
| Ongoing: | no |
| Previous Election: | 1962 United States Senate election in Colorado |
| Previous Year: | 1962 |
| Next Election: | 1974 United States Senate election in Colorado |
| Next Year: | 1974 |
| Election Date: | November 5, 1968 |
| Image1: | PHDominick.jpg |
| Nominee1: | Peter Dominick |
| Party1: | Republican Party (US) |
| Popular Vote1: | 459,952 |
| Percentage1: | 58.55% |
| Party2: | Democratic Party (US) |
| Popular Vote2: | 325,584 |
| Percentage2: | 41.45% |
| Map Size: | 250px |
| U.S. Senator | |
| Before Party: | Republican Party (US) |
| After Party: | Republican Party (US) |
The 1968 United States Senate election in Colorado took place on November 5, 1968. Incumbent Republican U.S. Senator Peter Dominick was re-elected to a second term in office over Democratic ex-Governor Stephen McNichols. Peter Dominick defeated Stephen McNichols in a landslide despite Richard Nixon, a fellow Republican to Peter Dominick, winning the state narrowly over Hubert Humphrey in the concurrent presidential election.