| Year: | 1968 |
| Team: | Southern Miss Southerners |
| Sport: | football |
| Conference: | Independent |
| Record: | 4–6 |
| Head Coach: | Thad Vann |
| Hc Year: | 20th |
| Stadium: | Faulkner Field |
The 1968 Southern Miss Southerners football team was an American football team that represented the University of Southern Mississippi as an independent during the 1968 NCAA University Division football season. In their twentieth year under head coach Thad Vann, the team compiled a 4–6 record.[1]