| Division: | II |
| Year: | 1968 |
| Teams: | 36 |
| Finalfourcity: | Evansville, Indiana |
| Champions: | Kentucky Wesleyan Panthers |
| Titlecount: | 2nd |
| Runnerup: | Indiana State Sycamores |
| Gamecount: | 1st |
| Semifinal1: | Trinity (TX) Tigers |
| Finalfourcount: | 1st |
| Semifinal2: | Ashland Eagles |
| Finalfourcount2: | 1st |
| Coach: | Bob Daniels |
| Coachcount: | 1st |
| Mop: | Jerry Newsom |
| Mopteam: | Indiana State |
| Attendance: | 33,899 |
The 1968 NCAA College Division basketball tournament involved 36 schools playing in a single-elimination tournament to determine the national champion of men's NCAA College Division college basketball as a culmination of the 1967–68 NCAA College Division men's basketball season. It was won by Kentucky Wesleyan College, with Indiana State's Jerry Newsom named Most Outstanding Player. Uniquely, Indiana State has finished as the National Runner-up in the (1946 and 1948) NAIA Tournaments, the (1979) NCAA Division I Tournament, and the 1968 NCAA Division II Tournament.
| School | Outcome | |
|---|---|---|
| American International | Regional Champion | |
| Assumption | Fifth Place* | |
| Bridgeport | Third Place* | |
| Buffalo State | Runner-up | |
| Le Moyne | Seventh Place* | |
| Northeastern | Fifth Place* | |
| Rochester | Third Place* | |
| Springfield | Seventh Place* | |
| School | Outcome | |
|---|---|---|
| Bethune–Cookman | Fourth Place | |
| Kentucky Wesleyan | Regional Champion | |
| Oglethorpe | Third Place | |
| Union (TN) | Runner-up | |
| School | Outcome | |
|---|---|---|
| Cheyney | Regional Champion | |
| Muhlenberg | Fourth Place | |
| Philadelphia Textile | Third Place | |
| Wagner | Runner-up | |
| School | Outcome | |
|---|---|---|
| Ashland | Regional Champion | |
| Denison | Third Place | |
| Norfolk State | Runner-up | |
| Roanoke | Fourth Place | |
| School | Outcome | |
|---|---|---|
| Evansville | Regional Champion | |
| Lincoln (MO) | Third Place | |
| Southern Colorado | Fourth Place | |
| SW Missouri State | Runner-up | |
| School | Outcome | |
|---|---|---|
| Jackson State | Third Place | |
| McNeese State | Fourth Place | |
| Pan American | Runner-up | |
| Trinity (TX) | Regional Champion | |
| School | Outcome | |
|---|---|---|
| DePauw | Fourth Place | |
| Illinois State | Runner-up | |
| Indiana State | Regional Champion | |
| South Dakota State | Third Place | |
| School | Outcome | |
|---|---|---|
| Nevada Southern | Regional Champion | |
| San Diego State | Third Place | |
| UC Davis | Fourth Place | |
| UC Irvine | Runner-up | |
*indicates a tie
Locations: Assumption College Gymnasium (Section A), University of Rochester Palestra (Section B) and Henry A. Butova Gymnasium (Regional final)
Hosts: Assumption College (Section A), University of Rochester (Section B) and American International College (Regional final)
Location: unknown Host: Union University
Location: Bollman Center Host: Cheyney State College
Location: Kates Gymnasium Host: Ashland University
Location: McDonald Hall and Arena Host: Southwest Missouri State University
Location: Memorial Gym Host: McNeese State University
Location: Horton Field House Host: Illinois State University
Location: Peterson Gym Host: San Diego State College
*denotes each overtime played
Location: Roberts Municipal Stadium Host: University of Evansville
*denotes each overtime played