| Election Name: | 1968 Missouri Secretary of State election |
| Country: | Missouri |
| Type: | Presidential |
| Ongoing: | no |
| Previous Election: | 1964 Missouri Secretary of State election |
| Previous Year: | 1964 |
| Next Election: | 1972 Missouri Secretary of State election |
| Next Year: | 1972 |
| Election Date: | 5 November 1968 |
| Nominee1: | James Kirkpatrick |
| Party1: | Democratic Party (United States) |
| Popular Vote1: | 995,742 |
| Percentage1: | 58.73% |
| Nominee2: | Murray C. Colbert |
| Party2: | Republican Party (United States) |
| Popular Vote2: | 699,765 |
| Percentage2: | 41.27% |
| Secretary of State | |
| Before Election: | James Kirkpatrick |
| Before Party: | Democratic Party (United States) |
| After Election: | James Kirkpatrick |
| After Party: | Democratic Party (United States) |
The 1968 Missouri Secretary of State election was held on 5 November 1968 in order to elect the secretary of state of Missouri. Democratic nominee and incumbent secretary of state James Kirkpatrick defeated Republican nominee Murray C. Colbert.[1]
On election day, 5 November 1968, Democratic nominee James Kirkpatrick won re-election by a margin of 295,977 votes against his opponent Republican nominee Murray C. Colbert, thereby retaining Democratic control over the office of secretary of state. Kirkpatrick was sworn in for his second term on 13 January 1969.[2]