First-seeded Bill Bowrey won in the final 7–5, 2–6, 9–7, 6–4 against Juan Gisbert Sr. to win the men's singles tennis title at the 1968 Australian Championships. Roy Emerson was the defending champion but did not compete that year.
A champion seed is indicated in bold text while text in italics indicates the round in which that seed was eliminated. The joint first seeds received a bye to the second round.