| Year: | 1965 |
| Team: | Tulane Green Wave |
| Sport: | football |
| Conference: | Southeastern Conference |
| Short Conf: | SEC |
| Record: | 2–8 |
| Conf Record: | 1–5 |
| Head Coach: | Tommy O'Boyle |
| Hc Year: | 4th |
| Stadium: | Tulane Stadium |
The 1965 Tulane Green Wave football team was an American football team that represented Tulane University during the 1965 NCAA University Division football season as a member of the Southeastern Conference. In their fourth year under head coach Tommy O'Boyle, the team compiled a 2–8 record. This marked the final season Tulane competed as a member of the Southeastern Conference as University President Herbert E. Longenecker announced their formal withdrawal from SEC competition on December 31, 1964, effective June 30, 1966.[1]
The Green Wave competed as an independent for the next 30 seasons before joining Conference USA in 1996.