| Sport: | soccer |
| Year: | 1965 |
| Team: | Saint Louis Billikens |
| Conference: | Independent |
| Record: | 14–0 |
| Conf Record: | N/A |
| Head Coach: | Bob Guelker |
| Hc Year: | 8th |
| Tourney: | NCAA Tournament |
| Tourney Result: | W 1–0 vs. Michigan State |
| Champion: | National Champions |
| Prev Year: | 1964 |
| Next Year: | 1966 |
The 1965 Saint Louis Billikens men's soccer team represented Saint Louis University during the 1965 NCAA soccer season. The Billikens won their fifth NCAA title this season. It was the eighth ever season the Billikens fielded a men's varsity soccer team.
|-!colspan=6 style=""| Regular season|-|-!colspan=6 style=""| NCAA Tournament|-|-