| Season: | 1965 |
| Manager: |  José Poy Jim López |
| Mgrtitle: | Manager |
| Chairman: |  Laudo Natel |
| Chrtitle: | Chairman |
| League: | Torneio Rio-São Paulo |
| League Result: | 6th |
| Cup1: | Campeonato Paulista |
| Cup1 Result: | 5th |
| Prevseason: | 1964 |
| Nextseason: | 1966 |
The 1965 football season was São Paulo's 36th season since club's existence.
| Games played | 74 (16 Torneio Rio-São Paulo, 40 Campeonato Paulista, 18 Friendly match) |
| Games won | 31 (8 Torneio Rio-São Paulo, 13 Campeonato Paulista, 10 Friendly match) |
| Games drawn | 16 (2 Torneio Rio-São Paulo, 7 Campeonato Paulista, 7 Friendly match) |
| Games lost | 17 (6 Torneio Rio-São Paulo, 10 Campeonato Paulista, 1 Friendly match) |
| Goals scored | 119 |
| Goals conceded | 83 |
| Goal difference | +36 |
| Best result | 8–0 (H) v Noroeste - Campeonato Paulista - 1965.11.07 |
| Worst result | 0–5 (A) v Botafogo - Torneio Rio-São Paulo - 1965.05.15 0–5 (A) v Palmeiras - Torneio Rio-São Paulo - 1965.05.19 |
| Most appearances | |
| Top scorer | |
| width=60 | Final Position | width=60 | Points | width=60 | Matches | width=60 | Wins | width=60 | Draws | width=60 | Losses | width=60 | Goals For | width=60 | Goals Away | width=60 | Win% |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 6th | 16 | 16 | 7 | 2 | 7 | 32 | 33 | 50% |
See main article: 1965 Campeonato Paulista.
| width=60 | Final Position | width=60 | Points | width=60 | Matches | width=60 | Wins | width=60 | Draws | width=60 | Losses | width=60 | Goals For | width=60 | Goals Away | width=60 | Win% |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 5th | 33 | 30 | 13 | 7 | 10 | 52 | 32 | 55% |