| Year: | 1965 |
| Team: | Drexel Dragons |
| Sport: | football |
| Conference: | Middle Atlantic Conference |
| Division: | Southern College Division |
| Short Conf: | MAC |
| Record: | 6–2 |
| Conf Record: | 4–2 |
| Head Coach: | Tom Grebis |
| Hc Year: | 5th |
| Stadium: | Drexel Field |
The 1965 Drexel Dragons football team represented the Drexel Institute of Technology (renamed Drexel University in 1970) as a member of the Middle Atlantic Conference during the 1965 NCAA College Division football season. Tom Grebis was the team's head coach.