| Tourney Name: | European Cup |
| Year: | 1965–66 |
| Size: | 300px |
| Dates: | 8 September 1965 – 11 May 1966 |
| Num Teams: | 31 |
| Champion Other: |  Real Madrid |
| Count: | 6 |
| Second Other: | Partizan |
| Matches: | 58 |
| Goals: | 224 |
| Attendance: | 1599799 |
| Top Scorer: | Florián Albert (Ferencváros) Eusébio (Benfica) 7 goals each |
| Prevseason: | 1964–65 |
| Nextseason: | 1966–67 |
The 1965–66 season of the European Cup football club tournament was won by Real Madrid, winners of the first five European Cups from 1956 to 1960, for the sixth time in a close final against Partizan. Real Madrid eliminated title-holders Internazionale in the semi-finals.
|}Note: Starting in the 1963–64 tournament, only the title holder, Internazionale, joined directly in the first round. They were the only Italian team to enter, while Cyprus re-entered its champion thus keeping the number of participants at 31.
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Real Madrid won 6–2 on aggregate.----Kilmarnock won 1–0 on aggregate.----Anderlecht won 5–1 on aggregate.----Derry City won 8–6 on aggregate.----Panathinaikos won 4–2 on aggregate.----Ferencváros won 13–2 on aggregate.----Dinamo București won 7–2 on aggregate.----Manchester United won 9–2 on aggregate.----Vorwärts Berlin won 3–1 on aggregate.----Benfica won 18–0 on aggregate.----Levski Sofia won 7–2 on aggregate.----Sparta Prague won 4–0 on aggregate.----Górnik Zabrze won 5–2 on aggregate.----Werder Bremen won 10–0 on aggregate.----Partizan won 4–2 on aggregate.
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Anderlecht won 9–0 on aggregate.----Real Madrid won 7–3 on aggregate.----Internazionale won 3–2 on aggregate.----Ferencváros won 3–1 on aggregate.----Sparta Prague won 5–1 on aggregate.----Partizan won 3–1 on aggregate.----Manchester United won 5–1 on aggregate.----Benfica won 5–4 on aggregate.
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Real Madrid won 4–3 on aggregate.----Internazionale won 5–1 on aggregate.----Partizan won 6–4 on aggregate.----Manchester United won 8–3 on aggregate.
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Real Madrid won 2–1 on aggregate.----Partizan won 2–1 on aggregate.
See main article: 1966 European Cup Final.
The top scorers from the 1965–66 European Cup (including preliminary round) are as follows:
