| Competition: | Liga Leumit |
| Season: | 1965–66 |
| Winners: | Hapoel Tel Aviv 6th title |
| Relegated: | Maccabi Petah Tikva Beitar Tel Aviv |
| League Topscorer: | Moshe Romano Mordechai Spiegler (17) |
| Prevseason: | 1964–65 |
| Nextseason: | 1966–68 |
The 1965–66 Liga Leumit season saw Hapoel Tel Aviv crowned champions and qualify for the first Asian Club Championships. Moshe Romano (Shimshon Tel Aviv) and Mordechai Spiegler (Maccabi Netanya) were the joint top scorers with 17 goals each.
Maccabi Petah Tikva and Beitar Tel Aviv were relegated to Liga Alef.
Prior to the season the IFA decided to allow substitutions of one player and one goalkeeper during matches.[1]