| Mode: | Basketball |
| Year: | 1965–66 |
| Team: | Drexel Dragons |
| Conference: | Middle Atlantic Conferences |
| Division: | College–Southern |
| Short Conf: | MAC |
| Record: | 20–4 |
| Conf Record: | 12–0 |
| Head Coach: | Samuel Cozen |
| Hc Year: | 14th |
| Stadium: | Sayre High School |
| Champion: | MAC College–Southern regular season champions |
| Bowl: | NCAA tournament Regional semifinals |
| Bowl Result: | L 54–62 |
The 1965–66 Drexel Dragons men's basketball team represented Drexel Institute of Technology during the 1965–66 men's basketball season. The Dragons, led by 14th year head coach Samuel Cozen, played their home games at Sayre High School and were members of the College–Southern division of the Middle Atlantic Conferences (MAC).
The team finished the regular season 19–1, and finished in 1st place in the MAC in the regular season.
|-!colspan=9 style="background:#F8B800; color:#002663;"| Regular season|-|-!colspan=9 style="background:#F8B800; color:#002663;"| 1966 Middle Atlantic Conference men's basketball tournament|-!colspan=9 style="background:#F8B800; color:#002663;"| 1966 NCAA College Division basketball tournament