| Year: | 1964 |
| Team: | SMU Mustangs |
| Sport: | football |
| Conference: | Southwest Conference |
| Short Conf: | SWC |
| Record: | 1–9 |
| Conf Record: | 0–7 |
| Head Coach: | Hayden Fry |
| Hc Year: | 3rd |
The 1964 SMU Mustangs football team represented Southern Methodist University (SMU) as a member of the Southwest Conference (SWC) during the 1964 NCAA University Division football season. Led by third-year head coach Hayden Fry, the Mustangs compiled an overall record of 1–9 with a conference mark of 0–7, placing last out of eight teams in the SWC.