| Dates: | 18 April 1964 – 20 December 1964 |
| Winners: | Universidad de Chile (5th title) |
| Relegated: | Ferrobádminton |
| Matches: | 306 |
| Total Goals: | 967 |
| Continentalcup1: | 1965 Copa Campeones |
| Continentalcup1 Qualifiers: | Universidad de Chile |
| League Topscorer: | Daniel Escudero (25) |
| Highest Attendance: | 73,801 |
| Attendance: | 2,931,965 |
| Average Attendance: | 9,581 |
| Prevseason: | 1963 |
| Nextseason: | 1965 |
The 1964 Campeonato Nacional de Fútbol Profesional, was the 32nd season of top-flight football in Chile. Universidad de Chile won their fourth title, also qualifying for the 1965 Copa de Campeones.[1]