| 1964–65 Cuban National Series | |
| League: | Cuban National Series |
| Sport: | Baseball |
| No Of Games: | 39 |
| No Of Teams: | 4 |
| Season: | Regular season |
| Season Champ Name: | Champion |
| Season Champs: | Industriales (25–14) |
| Seasonslistnames: | SNB |
| Prevseason Link: | 1963–64 Cuban National Series |
| Prevseason Year: | 1963–64 |
| Nextseason Link: | 1965–66 Cuban National Series |
| Nextseason Year: | 1965–66 |
Industriales began to make a habit of Cuban National Series titles during the 1964-65 season, the fourth installment of Cuba's new post-revolutionary amateur baseball league. The team, representing Havana, won its third straight title.
| Team | W | L | Pct. | GB | |
|---|---|---|---|---|---|
| 25 | 14 | .641 | - | ||
| Occidentales | 21 | 18 | .538 | 4 | |
| Granjeros | 18 | 21 | .461 | 7 | |
| Orientales | 14 | 25 | .359 | 8 |
Note: Granjeros had been named Azucareros prior to this season.