| Competition: | Segunda División de México |
| Season: | 1963–64 |
| Winners: | Cruz Azul (1st Title) |
| Matches: | 240 |
| Total Goals: | 903 |
| Prevseason: | 1962–63 |
| Nextseason: | 1964–65 |
The 1963–64 Mexican Segunda División was the 14th season of the Mexican Segunda División. The season started on 29 June 1963 and concluded on 7 February 1964. It was won by Cruz Azul. For the following season, the Primera División had an expansion from 14 to 16 teams, for which a promotion playoff was played at the end of this season.
| Club | City | Stadium | |
|---|---|---|---|
| Celaya | Celaya | Estadio Miguel Alemán Valdés | |
| Cruz Azul | Jasso | Estadio 10 de Diciembre | |
| La Piedad | La Piedad | Estadio Juan N. López | |
| Laguna | Torreón | Estadio San Isidro | |
| Nuevo León | Monterrey | Estadio Tecnológico | |
| Orizaba | Orizaba | Estadio Socum | |
| Pachuca | Pachuca | Estadio Revolución Mexicana | |
| Poza Rica | Poza Rica | Parque Jaime J. Merino | |
| Refinería Madero | Ciudad Madero | Estadio Tampico | |
| Tampico | Tampico | ||
| Tepic | Tepic | Estadio Nicolás Álvarez Ortega | |
| Texcoco | Texcoco | Estadio Municipal de Texcoco | |
| Torreón | Torreón | Estadio Revolución | |
| Veracruz | Veracruz | Parque Deportivo Veracruzano | |
| Ciudad Victoria | Ciudad Victoria | Estadio Marte R. Gómez | |
| Zamora | Zamora | Estadio Moctezuma |
In order to increase the number of team from 14 to 16 for the 1964–65 season the league made a playoff. The playoff was composed of the lowest team from Primera division and the 2nd-5th teams in the standings from Segunda Division as Cruz Azul had earned automatic promotion. The playoff was played between January 16 and February 6, 1964. All games were played in Estadio Olímpico Universitario, Mexico City.