| National Challenge Cup | |
| Year: | 1961 |
| Country: |  United States |
| Date: | --> |
| Defending Champions: | Philadelphia Ukrainian Nationals |
| Winners: | Philadelphia Ukrainian Nationals |
| Count: | 2 |
| Second: | Los Angeles Scots |
| Semifinal1: | --> |
| Semifinal2: | --> |
| Prev Season: | 1960 |
| Next Season: | 1962 |
The 1961 National Challenge Cup was the 48th edition of the USSFA's annual open soccer championship. The Philadelphia Ukrainians defeated the Los Angeles Scots to win.