| Election Name: | 1960 United States Senate election in Tennessee |
| Country: | Tennessee |
| Type: | presidential |
| Ongoing: | no |
| Previous Election: | 1954 United States Senate election in Tennessee |
| Previous Year: | 1954 |
| Next Election: | 1964 United States Senate special election in Tennessee |
| Next Year: | 1964 (special) |
| Election Date: | November 8, 1960 |
| Image1: | SenatorKefauver(D-TN).jpg |
| Nominee1: | Estes Kefauver |
| Party1: | Democratic Party (US) |
| Popular Vote1: | 594,460 |
| Percentage1: | 71.75% |
| Nominee2: | A. Bradley Frazier |
| Party2: | Republican Party (US) |
| Popular Vote2: | 234,053 |
| Percentage2: | 28.25% |
| Senator | |
| Before Election: | Estes Kefauver |
| Before Party: | Democratic Party (US) |
| After Election: | Estes Kefauver |
| After Party: | Democratic Party (US) |
The 1960 United States Senate election in Tennessee took place on November 8, 1960, concurrently with the U.S. presidential election, as well as elections to the United States Senate in other states as well as elections to the United States House of Representatives and various state and local elections. Incumbent Democratic Senator Estes Kefauver won re-election, defeating Republican candidate A. Bradley Frazier.