| Election Name: | 1960 United States Senate election in Mississippi |
| Country: | Mississippi |
| Flag Image: | Flag of Mississippi (1894-1996).svg |
| Type: | presidential |
| Ongoing: | no |
| Previous Election: | 1954 United States Senate election in Mississippi |
| Previous Year: | 1954 |
| Next Election: | 1966 United States Senate election in Mississippi |
| Next Year: | 1966 |
| Election Date: | November 8, 1960 |
| Nominee1: | James Eastland |
| Party1: | Democratic Party (United States) |
| Popular Vote1: | 244,341 |
| Percentage1: | 91.81% |
| Nominee2: | Joe Moore |
| Party2: | Republican Party (United States) |
| Popular Vote2: | 21,807 |
| Percentage2: | 8.19% |
| Map Size: | 255px |
| U.S. Senator | |
| Before Election: | James Eastland |
| Before Party: | Democratic Party (United States) |
| After Election: | James Eastland |
| After Party: | Democratic Party (United States) |
The 1960 United States Senate election in Mississippi was held on November 8, 1960.
Incumbent Senator James Eastland was re-elected to a fourth term in office against nominal opposition. The primary race attracted little attention and as was typical of elections in the South at this time, the general election was a foregone conclusion in favor of the Democratic candidate, Eastland.[1]
Moore was unopposed for the Republican nomination.