| Competition: | Primera División de México |
| Season: | 1960–61 |
| Winners: | Guadalajara (4th title) |
| Relegated: | Celaya |
| Matches: | 182 |
| Total Goals: | 510 |
| Prevseason: | 1959–60 |
| Nextseason: | 1961–62 |
Statistics of the Primera División de México for the 1960–61 season.
Monterrey was promoted to Primera División.
The season was contested by 14 teams, and Guadalajara won the championship and becomes first team to win three consecutive championships.
Celaya was relegated to Segunda División.