| Score: | 6–4, 6–3 |
| Draw: | 80 (5) |
| Seeds: | 4 |
| After Name: | Wimbledon Championships – Mixed doubles |
| Before Name: | Wimbledon Championships – Mixed doubles |
| Type: | grand slam |
See main article: 1959 Wimbledon Championships. Bob Howe and Lorraine Coghlan were the defending champions, but Coghlan did not compete. Howe partnered with Sally Moore but lost in the quarterfinals to Bob Mark and Jeanne Arth.
Rod Laver and Darlene Hard defeated Neale Fraser and Maria Bueno in the final, 6–4, 6–3 to win the mixed doubles tennis title at the 1959 Wimbledon Championships.[1]
See also: 1 and 1. 
Billy Knight / 
Yola Ramírez (semifinals)
See also: 2 and 8. 
Neale Fraser / 
Maria Bueno (final)
See also: 3 and 3. Rod Laver / 
Darlene Hard (champions)
See also: 4 and 6. Bob Howe / Sally Moore (quarterfinals)