| Year: | 1959 |
| Team: | Vanderbilt Commodores |
| Sport: | football |
| Conference: | Southeastern Conference |
| Short Conf: | SEC |
| Record: | 5–3–2 |
| Conf Record: | 3–2–2 |
| Head Coach: | Art Guepe |
| Hc Year: | 7th |
| Stadium: | Dudley Field |
The 1959 Vanderbilt Commodores football team represented Vanderbilt University in the 1959 college football season. The Commodores were led by head coach Art Guepe in his seventh season and finished the season with a record of five wins, three losses and two ties (5–3–2 overall, 3–2–2 in the SEC).