| Year: | 1959 |
| Competition: | VFL |
| Home: | |
| Home Score: | 17.13 (115) |
| Away: | |
| Away Score: | 11.12 (78) |
| Home Abbr: | MEL |
| Away Abbr: | ESS |
| Home Qtr1: | 1.4 (10) |
| Home Qtr2: | 8.5 (53) |
| Home Qtr3: | 11.10 (76) |
| Home Qtr4: | 17.13 (115) |
| Away Qtr1: | 3.5 (23) |
| Away Qtr2: | 7.8 (50) |
| Away Qtr3: | 10.10 (70) |
| Away Qtr4: | 11.12 (78) |
| Date: | 26 September 1959 |
| Attendance: | 103,506 |
| Stadium: | Melbourne Cricket Ground |
| Last: | 1958 |
| Next: | 1960 |
The 1959 VFL Grand Final was an Australian rules football game contested between the Melbourne Football Club and Essendon Football Club, held at the Melbourne Cricket Ground on 20 September 1959. It was the 62nd annual Grand Final of the Victorian Football League, staged to determine the premiers for the 1959 VFL season. The match, attended by 103,506 spectators, was won by Melbourne by 37 points, marking that club's tenth premiership victory.
This was Melbourne's sixth successive Grand Final appearance. It was the second time in three years in which the two teams met in a Grand Final, with Melbourne also having won the 1957 VFL Grand Final.
Melbourne:
| Essendon:
|