| Year: | 1959 |
| Team: | Middle Tennessee Blue Raiders |
| Sport: | football |
| Conference: | Ohio Valley Conference |
| Short Conf: | OVC |
| Record: | 10–0–1 |
| Conf Record: | 5–0–1 |
| Head Coach: | Charles M. Murphy |
| Hc Year: | 13th |
| Captain: | B. Pitts, Brady Luckett |
| Stadium: | Horace Jones Field |
| Champion: | OVC co-champion Tangerine Bowl champion |
| Bowl: | Tangerine Bowl |
| Bowl Result: | W 21–12 vs. |
The 1959 Middle Tennessee Blue Raiders football team represented the Middle Tennessee State College—now known as Middle Tennessee State University—as a member of the Ohio Valley Conference (OVC) during the 1959 college football season. Led by 13th-year head coach Charles M. Murphy, the Blue Raiders compiled an overall record of 10–0–1 with a mark of 5–0–1 in conference play, sharing the OVC title with . Middle Tennessee was invited to the Tangerine Bowl, where they beat . The team's captains were B. Pitts and Brady Luckett.[1]