| Competition: | Segunda División |
| Season: | 1959–60 |
| Winners: | Real Santander Mallorca |
| Promoted: | Real Santander Mallorca |
| Relegated: | Alavés Recreativo Avilés Atlético Almería Ferrol Badajoz |
| League Topscorer: | José Paredes (25 goals) |
| Best Goalkeeper: | Ricardo Zamora (0.67 goals/match) |
| Biggest Home Win: | (25 October 1959) (26 December 1959) |
| Biggest Away Win: | (20 March 1960) |
| Highest Scoring: | (6 December 1959) |
| Matches: | 480 |
| Total Goals: | 1508 |
| Prevseason: | 1958–59 |
| Nextseason: | 1960–61 |
The 1959–60 Segunda División season was the 29th since its establishment and was played between 12 September 1959 and 17 April 1960.
32 teams joined the league, including two relegated from the 1958–59 La Liga and 5 promoted from the 1958–59 Tercera División.
| Club | City | Stadium |
|---|---|---|
| Deportivo Alavés | Vitoria | Mendizorroza |
| Real Avilés CF | Avilés | La Exposición |
| Baracaldo Altos Hornos | Baracaldo | Lasesarre |
| CD Basconia | Basauri | Pedro López Cortázar |
| RC Celta de Vigo | Vigo | Balaídos |
| CD Condal | Barcelona | Les Corts |
| Cultural y Deportiva Leonesa | León | La Puentecilla |
| RC Deportivo La Coruña | La Coruña | Riazor |
| Club Ferrol | Ferrol | Manuel Rivera |
| Real Gijón CF | Gijón | El Molinón |
| SD Indauchu | Bilbao | Garellano |
| CD Orense | Orense | José Antonio |
| CD Sabadell FC | Sabadell | Cruz Alta |
| Real Santander SD | Santander | El Sardinero |
| Club Sestao | Sestao | Las Llanas |
| CD Tarrasa | Tarrasa | Obispo Irurita |
| Goalscorers | Goals | Team |
|---|---|---|
 Cesáreo Rivera | 23 | Ourense |
| Nicolás Mentxaka | 19 | Baracaldo |
| 17 | Real Santander | |
| Javier Barrena | 16 | Indauchu |
| Lolo Gómez | 15 | Celta Vigo |
| Goalkeeper | Goals | Matches | Average | Team | |
|---|---|---|---|---|---|
| Padrón | 37 | 30 | Celta Vigo | ||
| Gelucho | 33 | 25 | Ourense | ||
| Juan Visa | 34 | 22 | Tarrasa | ||
| Juan Emery | 46 | 29 | Deportivo La Coruña | ||
| Manuel Barea | 34 | 20 | Real Gijón |
| Goalscorers | Goals | Team |
|---|---|---|
| José Paredes | 25 | Levante |
 Fritz Hollaus | 18 | Rayo Vallecano |
| 16 | Plus Ultra | |
| Quirro | 16 | Recreativo |
| Manuel Haro | 15 | Jaén |
| Goalkeeper | Goals | Matches | Average | Team | |
|---|---|---|---|---|---|
| Ricardo Zamora | 18 | 27 | Mallorca | ||
| José Campillo | 34 | 30 | Murcia | ||
| Félix Arrizabalaga | 32 | 27 | Mestalla | ||
| Lorenzo Zúnica | 35 | 29 | Atlético Ceuta | ||
| José Bermúdez | 37 | 30 | Jaén |