| Election Name: | 1958 United States Senate election in Virginia |
| Country: | Virginia |
| Type: | presidential |
| Previous Election: | 1952 United States Senate election in Virginia |
| Previous Year: | 1952 |
| Next Election: | 1964 United States Senate election in Virginia |
| Next Year: | 1964 |
| Election Date: | November 4, 1958 |
| Image1: | Harry F. Byrd (cropped).jpg |
| Nominee1: | Harry F. Byrd |
| Party1: | Democratic Party (United States) |
| Popular Vote1: | 317,221 |
| Percentage1: | 69.32% |
| Nominee2: | Louise Wensel |
| Party2: | Independent (US) |
| Popular Vote2: | 120,224 |
| Percentage2: | 26.27% |
| Map Size: | 300px |
| U.S. senator | |
| Before Election: | Harry F. Byrd |
| Before Party: | Democratic Party (US) |
| After Election: | Harry F. Byrd |
| After Party: | Democratic Party (US) |
The 1958 United States Senate election in Virginia was held on November 4, 1958. Incumbent Senator Harry F. Byrd, Sr. was re-elected to a sixth term after defeating Independent Louise Wensel and Social Democrat Clarke Robb.