| Election Name: | 1958 United States Senate election in Mississippi |
| Country: | Mississippi |
| Flag Image: | Flag of Mississippi (1894-1996).svg |
| Type: | Presidential |
| Ongoing: | no |
| Previous Election: | 1952 United States Senate election in Mississippi |
| Previous Year: | 1952 |
| Next Election: | 1964 United States Senate election in Mississippi |
| Next Year: | 1964 |
| Election Date: | November 4, 1958 |
| Image1: | File:John Stennis.jpg |
| Nominee1: | John C. Stennis |
| Party1: | Democratic Party (United States) |
| Popular Vote1: | 61,039 |
| Percentage1: | 100.00% |
| Map Size: | 255px |
| U.S. Senator | |
| Before Election: | John C. Stennis |
| Before Party: | Democratic Party (United States) |
| After Election: | John C. Stennis |
| After Party: | Democratic Party (United States) |
The 1958 United States Senate election in Mississippi took place on November 4, 1958. Incumbent Democratic U.S. Senator John C. Stennis was re-elected to a third term in office.
Because Stennis was unopposed in the general election, his victory in the August 26 primary was tantamount to election. Stennis was also unopposed in the primary.
The Democratic primary election was held on August 26, 1958.