| Election Name: | 1958 United States Senate election in Minnesota |
| Country: | Minnesota |
| Flag Year: | 1957 |
| Type: | presidential |
| Ongoing: | no |
| Previous Election: | 1952 United States Senate election in Minnesota |
| Previous Year: | 1952 |
| Next Election: | 1964 United States Senate election in Minnesota |
| Next Year: | 1964 |
| Election Date: | November 4, 1958 |
| Image1: | File:EugeneMcCarthy (cropped2).jpg |
| Nominee1: | Eugene J. McCarthy |
| Party1: | Democratic–Farmer–Labor Party (Minnesota) |
| Popular Vote1: | 608,847 |
| Percentage1: | 52.95% |
| Party2: | Republican Party (United States) |
| Popular Vote2: | 535,629 |
| Percentage2: | 46.58% |
| Map Size: | 270px |
| U.S. Senator | |
| Before Party: | Republican Party (United States) |
| After Party: | Democratic–Farmer–Labor Party (Minnesota) |
The 1958 United States Senate election in Minnesota took place on November 4, 1958. Democratic U.S. Representative Eugene McCarthy defeated incumbent Republican U.S. Senator Edward John Thye, who sought a third term. With his victory, McCarthy became the first Democrat ever to be popularly elected to Minnesota's Class 1 Senate seat, and marked the first time since 1859 that Democrats held both Senate seats in the state.