See main article: 1958 U.S. National Championships (tennis).
Defending champion Althea Gibson defeated Darlene Hard in the final, 3–6, 6–1, 6–2 to win the women's singles tennis title at the 1958 U.S. National Championships.[1]
The seeded players are listed below. Althea Gibson is the champion; others show in brackets the round in which they were eliminated.[2]