| Year: | 1958 |
| Team: | SMU Mustangs |
| Sport: | football |
| Conference: | Southwest Conference |
| Short Conf: | SWC |
| Coachrank: | 18 |
| Aprank: | 18 |
| Record: | 6–4 |
| Conf Record: | 4–2 |
| Head Coach: | Bill Meek |
| Hc Year: | 2nd |
| Captain: | Tom Koening |
| Stadium: | Cotton Bowl |
The 1958 SMU Mustangs football team represented Southern Methodist University (SMU) as a member of the Southwest Conference (SWC) during the 1958 college football season. Led by second-year head coach Bill Meek, the Mustangs compiled an overall record of 6–4 with a conference mark of 4–2, tying for second place in the SWC.