| Competition: | Primera División de México |
| Season: | 1958–59 |
| Winners: | Guadalajara (2nd title) |
| Relegated: | Cuautla |
| Continentalcup1: | Campeónato Centroamericano |
| Continentalcup1 Qualifiers: | Guadalajara |
| Matches: | 182 |
| Total Goals: | 584 |
| Prevseason: | 1957–58 |
| Nextseason: | 1959–60 |
Statistics of the Primera División de México for the 1958–59 season.
Celaya was promoted to Primera División.
The season was contested by 14 teams, and Guadalajara won the championship.
Cuautla was relegated to Segunda División.
Guadalajara qualified to the 1959 Campeonato Centroamericano.[1]
| Team | City | Stadium | |
|---|---|---|---|
| América | Mexico City | Olímpico Universitario | |
| Atlante | Mexico City | Ciudad de los Deportes | |
| Atlas | Guadalajara, Jalisco | Parque Oblatos | |
| Celaya | Celaya, Guanajuato | Miguel Alemán Valdés | |
| Cuautla | Cuautla, Morelos | El Almeal | |
| Guadalajara | Guadalajara, Jalisco | Parque Oblatos | |
| Irapuato | Irapuato, Guanajuato | Revolución | |
| León | León, Guanajuato | La Martinica | |
| Morelia | Morelia, Michoacán | Campo Morelia | |
| Necaxa | Mexico City | Olímpico Universitario | |
| Oro | Guadalajara, Jalisco | Parque Oblatos | |
| Toluca | Toluca, State of Mexico | Héctor Barraza | |
| Zacatepec | Zacatepec, Morelos | Campo del Ingenio | |
| Zamora | Zamora, Michoacán | Moctezuma |