| National Challenge Cup | |
| Year: | 1953 |
| Country: |  United States |
| Dates: | 1 March- 26 April 1953 |
| Defending Champions: | Harmarville Hurricanes |
| Winners: | Chicago Falcons |
| Count: | 1 |
| Second: | Harmarville Hurricanes |
| Semifinal1: | St. Louis Kutis S.C. |
| Semifinal2: | New York Americans |
| Prev Season: | 1952 |
| Next Season: | 1954 |
The 1953 National Challenge Cup was the 40th edition of the USSFA's annual open soccer championship. The Chicago Falcons defeated the Harmarville Hurricanes (a suburban Pittsburgh team) to win.