First-seeded Nancye Bolton defeated Thelma Long 6–1, 7–5 in the final to win the women's singles tennis title at the 1951 Australian Championships.
The seeded players are listed below. Nancye Bolton is the champion; others show the round in which they were eliminated.
Nancye Bolton (champion) Joyce Fitch (semifinals) Thelma Long (finalist) Mary Hawton (quarterfinals) Esme Ashford (semifinals) Nell Hopman (quarterfinals) Sadie Newcombe (second round) Beryl Penrose (quarterfinals)