| Election Name: | 1950 United States Senate election in Colorado |
| Country: | Colorado |
| Type: | presidential |
| Ongoing: | no |
| Previous Election: | 1944 United States Senate election in Colorado |
| Previous Year: | 1944 |
| Next Election: | 1956 United States Senate election in Colorado |
| Next Year: | 1956 |
| Election Date: | November 7, 1950 |
| Image1: | Eugene Millikin.jpg |
| Nominee1: | Eugene Millikin |
| Party1: | Republican Party (United States) |
| Popular Vote1: | 239,724 |
| Percentage1: | 53.25% |
| Nominee2: | John A. Carroll |
| Party2: | Democratic Party (United States) |
| Popular Vote2: | 210,442 |
| Percentage2: | 46.75% |
| Map Size: | 250px |
| U.S. Senator | |
| Before Election: | Eugene Millikin |
| Before Party: | Republican Party (United States) |
| After Election: | Eugene Millikin |
| After Party: | Republican Party (United States) |
The 1950 United States Senate election in Colorado took place on November 7, 1950. Incumbent Republican Senator Eugene Millikin ran for re-election to his second full term. He faced a strong challenge from Congressman John A. Carroll, the Democratic nominee, in the general election. Carroll ultimately lost, but despite facing considerable headwinds nationwide, held Millikin to the narrowest victory of his career.