| Season: | 1950 |
| Manager: |  Vicente Feola |
| Mgrtitle: | Manager |
| Chairman: | Cícero Pompeu de Toledo |
| Chrtitle: | Chairman |
| League: | Torneio Rio-São Paulo |
| League Result: | 6th |
| Cup1: | Campeonato Paulista |
| Cup1 Result: | Runners-up |
| Prevseason: | 1949 |
| Nextseason: | 1951 |
The 1950 football season was São Paulo's 21st season since the club's founding in 1930.
| Games played | 52 (7 Torneio Rio-São Paulo, 22 Campeonato Paulista, 23 Friendly match) |
| Games won | 30 (2 Torneio Rio-São Paulo, 13 Campeonato Paulista, 15 Friendly match) |
| Games drawn | 12 (1 Torneio Rio-São Paulo, 5 Campeonato Paulista, 6 Friendly match) |
| Games lost | 10 (4 Torneio Rio-São Paulo, 4 Campeonato Paulista, 2 Friendly match) |
| Goals scored | 139 |
| Goals conceded | 81 |
| Goal difference | +58 |
| Best result | 10–0 (H) v Guarani - Campeonato Paulista - 1950.11.11 |
| Worst result | 1–4 (A) v Corinthians - Torneio Rio-São Paulo - 1949.12.28 |
| Most appearances | |
| Top scorer | |