| Competition: | Luxembourg National Division |
| Season: | 1950–51 |
| Winners: | Jeunesse Esch (3rd title) |
| Matches: | 132 |
| Total Goals: | 532 |
| Highest Scoring: | Stade Dudelange 10–1 FCM Young Boys Diekirch |
| Prevseason: | 1949–50 |
| Nextseason: | 1951–52 |
The 1950–51 Luxembourg National Division was the 37th season of top level association football in Luxembourg.
It was performed in 12 teams, and Jeunesse Esch won the championship.