| Competition: | Segunda División de México |
| Season: | 1950–51 |
| Winners: | Zacatepec (1st title) |
| Matches: | 42 |
| Total Goals: | 124 |
| Nextseason: | 1951–52 |
The 1950-51 Segunda División de México season was the first tournament in this competition. It counted with the participation of seven teams.[1]
| Team | City | Stadium | |
|---|---|---|---|
| Irapuato F.C. | Irapuato, Guanajuato | Revolución | |
| C.D. Morelia | Morelia, Michoacán | Campo Morelia | |
| C.F. Pachuca | Pachuca, Hidalgo | Campo Margarito Ramírez | |
| Querétaro F.C. | Querétaro, Querétaro | Municipal de Querétaro | |
| Deportivo Toluca | Toluca, State of Mexico | Campo Patria | |
| Club Zacatepec | Zacatepec, Morelos | Parque del Ingenio | |
| C.D. Zamora | Zamora, Michoacán | Campo Aviación |