| Year: | 1949 |
| Team: | Jacksonville State Gamecocks |
| Sport: | football |
| Conference: | Alabama Intercollegiate Conference |
| Short Conf: | AIC |
| Record: | 6–3 |
| Conf Record: | 3–2 |
| Head Coach: | Don Salls |
| Hc Year: | 4th |
| Stadium: | College Bowl |
| Bowl: | Paper Bowl |
| Bowl Result: | W 12–7 vs. Livingston State |
The 1949 Jacksonville State Gamecocks football team represented Jacksonville State Teachers College (now known as Jacksonville State University) as a member of the Alabama Intercollegiate Conference (AIC) during the 1949 college football season. Led by fourth-year head coach Don Salls, the Gamecocks compiled an overall record of 6–3 with a mark of 3–2 in conference play, placing third in the AIC.