| Competition: | Segunda División |
| Season: | 1949–50 |
| Winners: | Alcoyano Real Santander |
| Promoted: | Real Santander Lérida Murcia Alcoyano |
| Relegated: | Erandio Elche Arosa Castellón |
| League Topscorer: | Pío Alonso (31 goals) |
| Best Goalkeeper: | Vicente Izquierdo (1 goal/match) |
| Biggest Home Win: | (4 September 1949) (20 November 1949) |
| Biggest Away Win: | (11 September 1949) (6 November 1949) (5 February 1950) (5 March 1950) |
| Highest Scoring: | (4 September 1949) |
| Matches: | 480 |
| Total Goals: | 1980 |
| Prevseason: | 1948–49 |
| Nextseason: | 1950–51 |
The 1949–50 Segunda División season was the 19th since its establishment and was played between 3 September 1949 and 30 April 1950.
32 teams joined the league, including two relegated from the 1948–49 La Liga and 18 promoted from the 1948–49 Tercera División.
| Club | City | Stadium |
|---|---|---|
| Arosa SC | Villagarcía de Arosa | La Lomba |
| CF Badalona | Badalona | Avenida de Navarra |
| Club Baracaldo | Baracaldo | Lasesarre |
| Club Erandio | Erandio | Ategorri |
| Club Ferrol | Ferrol | Inferniño |
| Gerona CF | Gerona | Vista Alegre |
| Real Gijón | Gijón | El Molinón |
| RS Gimnástica de Torrelavega | Torrelavega | El Malecón |
| UD Lérida | Lérida | Campo de Deportes |
| SG Lucense | Lugo | Los Miñones |
| CD Numancia | Soria | San Andrés |
| UD Orensana | Orense | O Couto |
| CA Osasuna | Pamplona | San Juan |
| CD Sabadell FC | Sabadell | Cruz Alta |
| Real Santander SD | Santander | El Sardinero |
| Zaragoza CF | Zaragoza | Torrero |
| Goalscorers | Goals | Team |
|---|---|---|
 Pío Alonso | 31 | Real Gijón |
| 28 | Gimnástica Torrelavega | |
| Joseíto | 25 | Real Santander |
| Manuel Badenes | 21 | Zaragoza |
| Sebastián Fustero | 18 | Lérida |
| Goalkeeper | Goals | Matches | Average | Team | |
|---|---|---|---|---|---|
| José Rivero | 38 | 29 | Lérida | ||
| Juan Delgado | 42 | 28 | Real Santander | ||
| José María Munárriz | 25 | 16 | Real Gijón | ||
| Manuel Lestón | 38 | 24 | Orensana | ||
| Higinio Martí | 20 | 11 | Zaragoza |
| Goalscorers | Goals | Team |
|---|---|---|
| Manuel del Toro | 25 | Murcia |
| 21 | Atlético Tetuán | |
| Juan Ayala | 21 | Linense |
| Cabillo | 19 | Alcoyano |
| Loren | 19 | Salamanca |
| Goalkeeper | Goals | Matches | Average | Team | |
|---|---|---|---|---|---|
| Vicente Izquierdo | 15 | 15 | Mestalla | ||
| Luis Martín | 39 | 30 | Alcoyano | ||
| Manuel Pachón | 39 | 30 | Atlético Tetuán | ||
| Juan Seva | 19 | 13 | Hércules | ||
| Paquillo | 19 | 12 | Real Córdoba |