| Election Name: | 1948 United States Senate election in Massachusetts |
| Country: | Massachusetts |
| Flag Year: | 1908 |
| Type: | presidential |
| Ongoing: | no |
| Previous Election: | 1944 United States Senate special election in Massachusetts |
| Previous Year: | 1944 (special) |
| Next Election: | 1954 United States Senate election in Massachusetts |
| Next Year: | 1954 |
| Election Date: | November 2, 1948 |
| Image1: | LeverettSaltonstall.jpg |
| Nominee1: | Leverett Saltonstall |
| Party1: | Republican Party (US) |
| Popular Vote1: | 1,088,475 |
| Percentage1: | 52.95% |
| Nominee2: | John I. Fitzgerald |
| Party2: | Democratic Party (US) |
| Popular Vote2: | 954,398 |
| Percentage2: | 46.43% |
| Senator | |
| Before Election: | Leverett Saltonstall |
| Before Party: | Republican Party (US) |
| After Election: | Leverett Saltonstall |
| After Party: | Republican Party (US) |
| Map Size: | 250px |
The United States Senate election of 1948 in Massachusetts was held on November 2, 1948, with Republican incumbent Leverett Saltonstall defeating his challengers.
Senator Saltonstall was unopposed for renomination.