| Competition: | Luxembourg National Division |
| Season: | 1948–49 |
| Winners: | CA Spora Luxembourg (8th title) |
| Matches: | 132 |
| Total Goals: | 507 |
| Highest Scoring: | Union Luxembourg 10–2 CS Pétange |
| Prevseason: | 1947–48 |
| Nextseason: | 1949–50 |
The 1948–49 Luxembourg National Division was the 35th season of top level association football in Luxembourg.
It was performed in 12 teams, and CA Spora Luxembourg won the championship.