| Year: | 1946 |
| Team: | Saint Louis Billikens |
| Sport: | football |
| Conference: | Missouri Valley Conference |
| Short Conf: | MVC |
| Record: | 4–6 |
| Conf Record: | 1–1 |
| Head Coach: | Dukes Duford |
| Hc Year: | 7th |
| Stadium: | Walsh Stadium |
The 1946 Saint Louis Billikens football team was an American football team that represented Saint Louis University as a member of the Missouri Valley Conference (MVC) during the 1946 college football season. In its seventh season under head coach Dukes Duford, the team compiled a 4–6 record (1–1 against MVC opponents), finished third in the conference, and was outscored by a total of 164 to 160.[1] The team played its home games at Walsh Stadium in St. Louis.