| Year: | 1946 |
| Team: | Loyola Lions |
| Sport: | football |
| Conference: | Independent |
| Record: | 5–4 |
| Head Coach: | Tony DeLellis |
| Hc Year: | 1st |
| Stadium: | Gilmore Stadium |
| Prev Year: | 1942 |
The 1946 Loyola Lions football team was an American football team that represented Loyola University of Los Angeles (now known as Loyola Marymount University) as an independent during the 1946 college football season. In their first and only season under head coach Tony DeLellis, the Lions compiled a 5–4 record.