| Type: | grand slam |
| Score: | 6–4, 6–4 |
| Draw: | 23 |
| Seeds: | 8 |
| Before Year: | 1940 |
First-seeded Nancye Bolton defeated Joyce Fitch 6–4, 6–4 in the final to win the women's singles tennis title at the 1946 Australian Championships.
The seeded players are listed below. Nancye Bolton is the champion; others show the round in which they were eliminated.
Nancye Bolton (champion) Nell Hopman (quarterfinals) Thelma Long (quarterfinals) Joan Hartigan (quarterfinals) Constance Wilson (semifinals) Alison Hattersley (second round) Dulcie Whittaker (quarterfinals) Joyce Fitch (finalist)