| Year: | 1945 |
| Team: | West Virginia State Yellow Jackets |
| Sport: | football |
| Conference: | Colored Intercollegiate Athletic Association |
| Short Conf: | CIAA |
| Record: | 5–1–2 |
| Conf Record: | 4–0–2 |
| Head Coach: | Mark Cardwell |
| Hc Year: | 1st |
| Stadium: | Lakin Field |
The 1945 West Virginia State Yellow Jackets football team was an American football team that represented West Virginia State University as a member of the Colored Intercollegiate Athletic Association (CIAA) during the 1945 college football season. In their first season under head coach Mark Cardwell, the team compiled a 5–1–2 record and outscored opponents by a total of 142 to 32.[1]
The team played its home games in Charleston, West Virginia, and at Lakin Field in Institute, West Virginia.