Second-seeded Sarah Palfrey Cooke defeated first-seeded Pauline Betz 3–6, 8–6, 6–4 in the final to win the women's singles tennis title at the 1945 U.S. National Championships.[1]
The eight seeded U.S. players are listed below. Sarah Palfrey Cooke is the champion; others show in brackets the round in which they were eliminated.[2] [3]
One foreign player was seeded.