| 1945 Tipperary Senior Hurling Championship | |
| Count: | 15 |
| Runners-Up: | Roscrea |
| Previous Year: | 1944 |
| Previous Tournament: | 1944 Tipperary Senior Hurling Championship |
| Next Year: | 1946 |
| Next Tournament: | 1946 Tipperary Senior Hurling Championship |
The 1945 Tipperary Senior Hurling Championship was the 55th staging of the Tipperary Senior Hurling Championship since its establishment by the Tipperary County Board in 1887.
Thurles Sarsfields were the defending champions.
Thurles Sarsfields won the championship after a defeat of Roscrea in the final.[1] It was their 15th championship title overall and their second title in succession.