| Year: | 1945 |
| Team: | Lafayette Leopards |
| Sport: | football |
| Conference: | Middle Three Conference |
| Short Conf: | Middle Three |
| Record: | 1–7–1 |
| Conf Record: | 1–1 |
| Head Coach: | Ben Wolfson |
| Hc Year: | 3rd |
| Captain: | Game captains |
| Stadium: | Fisher Field |
The 1945 Lafayette Leopards football team was an American football team that represented Lafayette College in the Middle Three Conference during the 1945 college football season. In its third and final season under head coach Ben Wolfson, the team compiled a 1–7–1 record.[1] The team was led by game captains and played home games at Fisher Field in Easton, Pennsylvania.[2]