| Election Name: | 1945 Detroit mayoral election |
| Type: | Presidential |
| Ongoing: | no |
| Previous Election: | 1943 Detroit mayoral election |
| Previous Year: | 1943 |
| Next Election: | 1947Detroit mayoral election |
| Next Year: | 1947 |
| Image1: | Edward Jeffries.JPG |
| Candidate1: | Edward J. Jeffries Jr. |
| Party1: | Nonpartisan candidate |
| Popular Vote1: | 274,802 |
| Percentage1: | 54.85% |
| Candidate2: | Richard Frankensteen |
| Party2: | Nonpartisan candidate |
| Popular Vote2: | 217,208 |
| Percentage2: | 43.35% |
| Mayor | |
| Before Election: | Edward J. Jeffries Jr. |
| After Election: | Edward J. Jeffries Jr. |
The Detroit mayoral election of 1945 took place on November 6, 1945. It saw the reelection of incumbent mayor Edward J. Jeffries Jr. to a fourth term.