| Year: | 1945 |
| Team: | Appalachian State Mountaineers |
| Sport: | football |
| Conference: | North State Conference |
| Short Conf: | NSC |
| Record: | 1–6 |
| Conf Record: | 1–3 |
| Head Coach: | Francis Hoover |
| Hc Year: | 1st |
| Stadium: | College Field |
| Prev Year: | 1942 |
The 1945 Appalachian State Mountaineers football team was an American football team that represented Appalachian State Teachers College (now known as Appalachian State University) as a member of the North State Conference during the 1945 college football season. In their only year under head coach Francis Hoover, the Mountaineers compiled an overall record of 1–6, with a mark of 1–3 in conference play, and finished 3rd in the NSC.